[Sleep regulation as a complex process]. / Regulyatsiya sna kak kompleksnyi protsess.

A retrospective analysis of views on the regulation of the «sleep-wakefulness¼ cycle from the reticular theory of sleep to the Saper's model was carried out. A modified version of the Saper's trigger made it possible to use the results of a comparative analysis of drugs used in the treatment of sleep disorders to develop new, comprehensive, effective approaches to the pharmacotherapy of the most common sleep disorders. It seems that this approach will be useful in the development of effective pharmacotherapy for sleep disorders.

[Anxiety and sleep in experiment and clinic]. / Vzaimootnosheniia trevogi i sna v éksperimente i klinike.

High anxiety is a genetically determined personal trait. It is produced by limbic system and other cerebral structures involved in maintenance of wakefulness and development of sleep. Analysis of experiments on the animals and clinic observations showed that animals and individuals with high personal anxiety have a high risk of anxiety disorders. Inhibition of GABA-benzodiazepine system which is typical for high anxiety dramatically influences sleep duration and sleep quality. Phenazepamum due to its anxiolytic properties deactivates the excitation focus in the brain, jugulates anxiety and normalize sleep.